This medication is a combination of two drugs, rosiglitazone and glimepiride. It is used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes (non-insulin-dependent diabetes). Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke.
You should only begin taking rosiglitazone/glimepiride when other drugs have not worked well or cannot be taken, and you do not wish to take pioglitazone-containing medications. If you are currently taking rosiglitazone/glimepiride and have good control of your blood sugars and no new side effects/symptoms, continue to take this medication as directed. Ask your doctor promptly about the risks and benefits of this medication, since a small number of people have had serious side effects (see Warning Section).
After November 18, 2011, only patients enrolled in the Avandia-Rosiglitazone Medicines Access Program may obtain and use rosiglitazone-containing products. Your doctor will need to register you with this program before you can receive your prescription. Only physicians enrolled in the Avandia-Rosiglitazone Medicines Access Program may prescribe rosiglitazone-containing products, and only certified mail-order pharmacies enrolled in the program may dispense them. Talk to your doctor or pharmacist for more details about the program.
Rosiglitazone belongs to a class of drugs known as thiazolidinediones or "glitazones". It works by helping to restore your body's proper response to insulin, thereby lowering your blood sugar.
Glimepiride belongs to a class of drugs known as sulfonylureas. It works by stimulating the release of your body's natural insulin.
How To Use
Read the Medication Guide provided by your pharmacist before you start taking this medication and each time you get a refill. If you have any questions, consult your doctor or pharmacist.
Take this medication by mouth, usually once daily with the first meal of the day or as directed by your doctor.
The dosage is based on your medical condition and response to therapy. Do not take more than 8 milligrams of rosiglitazone/4 milligrams of glimepiride per day.
Use this medication regularly in order to get the most benefit from it. Remember to take it at the same time each day. Monitor your blood sugar levels on a regular basis, and share the results with your doctor.
It may take up to 2-3 months before the full benefit of this drug takes effect.