Humulin R U-500 "Concentrated" Inj Uses and How to Use

  • Uses

    This man-made insulin product is the same as human insulin. It is used along with a proper diet and exercise program to control high blood sugar in people with diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke.

    This product is the concentrated form of regular insulin. It is used in people who require large doses of insulin (more than 200 units per day). It works right away like regular insulin but its effects last longer. In some people with diabetes, insulin may be used alone or with oral diabetes drugs (such as metformin).

    People with diabetes do not make enough insulin for their bodies to properly use the sugar in food. Eating a balanced diet, exercising regularly, and using your insulin as directed can help you live an active and healthy life.

    How To Use

    Read the Patient Information Leaflet provided by your pharmacist before you start using this insulin and each time you get a refill. If you have any questions, consult your doctor or pharmacist.

    This insulin must be injected. It is a high-strength concentrated liquid. Therefore, it is important that you learn all preparation and usage instructions, including how to measure the correct dose using the proper syringe, how to inject this medication properly, and how to self-manage your diabetes (such as monitoring blood sugar, recognizing and treating high/low blood sugar). Your health care professional will teach you how to use this medication. If you have any questions, consult your doctor, diabetes educator, or pharmacist.

    Wash your hands before measuring and injecting insulin. Before using, warm this drug to room temperature if it has been refrigerated. Do not inject cold insulin because this can be painful. The insulin container you are currently using can be kept at room temperature. (See also Storage section.)

    Before using, inspect this product visually for particles or discoloration. If either is present, do not use the insulin. Before injecting each dose, clean the injection site with rubbing alcohol. It is important to change the location of the injection site daily to avoid developing problem areas under the skin (lipodystrophy). Inject this medication under the skin of the abdomen, the thigh, or the back of the upper arm as directed by your doctor. Do not inject into a vein or muscle. Use this medication either 30-60 minutes before or immediately after a meal as directed by your doctor. Because this insulin can be fast-acting, not eating immediately after a dose of this insulin may lead to low blood sugar (hypoglycemia). After pulling out the needle, apply gentle pressure on the injection site. Do not rub the area.

    The dosage is based on your medical condition and response to treatment. Measure each dose very carefully because even small changes in the amount of insulin may have a large effect on your blood sugar levels.

    Use this medication regularly as directed by your doctor to get the most benefit from it. Carefully follow the insulin treatment plan, meal plan, and exercise program your doctor has recommended. Check your urine/blood sugar as directed by your doctor. Keep track of your results and share them with your doctor. This is very important in order to determine the correct insulin dose.

    If you are directed to inject this insulin with an infusion pump, read the instruction manual and directions that come with the infusion pump. If you have any questions, consult your doctor, diabetes educator, or pharmacist. Avoid exposing the pump or its tubing to direct sunlight or other heat sources.

    Do not change brands/types of insulin or syringes without directions on how to do so from your doctor. Do not reuse disposable needles and syringes. Learn how to store and discard needles and medical supplies safely. Consult your pharmacist.