This man-made insulin product is the same as human insulin. It is used along with a proper diet and exercise program to control high blood sugar in people with diabetes. Controlling high blood sugar helps prevent heart disease, strokes, kidney disease, circulation problems, blindness, and sexual function problems.
Human isophane insulin is an intermediate-acting insulin. It starts to work more slowly but lasts longer than regular insulin. Isophane insulin is often used in combination with a shorter-acting insulin. In some people with diabetes, insulin may be used alone or with other diabetes drugs (e.g., sulfonylureas like glyburide).
People with diabetes do not make enough insulin for their body to properly use the sugar in food. Eating a balanced diet, exercising regularly, and using your insulin as directed can help you live an active and healthy life.
How To Use
Read the Patient Information Leaflet before you start using this insulin and each time you get a refill. If you have any questions, consult your doctor or pharmacist.
This insulin must be injected. Learn all preparation and usage instructions, including how to measure the correct dose, how to inject this medication properly, and how to self-manage your diabetes (e.g., monitoring blood sugar, recognizing and treating high/low blood sugar). Your health care professional will teach you how to use this medication. If you have any questions, consult your doctor, diabetes educator, or pharmacist.
Wash your hands before measuring and injecting insulin. Before using, warm this drug to room temperature if it has been refrigerated. Do not inject cold insulin because this can be painful. The insulin container you are currently using can be kept at room temperature. The length of time you can store it at room temperature depends on the product. Consult your pharmacist. (See also Storage section.)
Gently roll the vial or cartridge, turning it upside down and back to mix the medication. Do not shake the container. Check the product visually for clumps or discoloration. If either is present, do not use the insulin. Isophane insulin should look evenly cloudy/milky after mixing. Do not use if you see clumps of white material, a "frosty" appearance, or particles stuck to the sides of the vial or cartridge.
Before injecting each dose, clean the injection site with rubbing alcohol. It is important to change the location of the injection site daily to prevent problem areas under the skin (lipodystrophy). Do not reuse the site for 2 weeks. Inject the medication quickly over 2-4 seconds under the skin of the thigh, abdomen, buttock, or back of the upper arm. If you inject too slowly (more than 5 seconds), the tip of the needle may become clogged and you may not get the correct dose. Do not inject into a vein. After pulling out the needle, apply gentle pressure on the injection site. Do not rub the area.
The dosage is based on your medical condition and response to therapy. Measure each dose very carefully because even small changes in the amount of insulin may have a large effect on your blood sugar levels.
Use this medication regularly as directed by your doctor to get the most benefit from it. Carefully follow the insulin treatment plan, meal plan, and exercise program your doctor has recommended. Check your urine/blood sugar as directed by your doctor. Keep track of your results and share them with your doctor. This is very important in order to determine the correct insulin dose.
This product may be mixed with regular insulin only. Always draw the regular insulin into the syringe first, then follow with the isophane insulin. Consult your pharmacist about which products may be mixed and about the proper method for mixing insulin. Never inject a mixture of different insulins into a vein.
Do not change brands/types of insulin, syringes, or needles without directions on how to do so from your doctor. Do not reuse disposable needles and syringes. Learn how to store and discard needles and medical supplies safely. Consult your pharmacist.