Protein Deficiency Diseases

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Protein C deficiency is a disorder characterized by an increased tendency to form blood clots.

Protein C is a vitamin-K-dependent anticoagulant protein manufactured in the liver and circulated in the plasma. Protein C inhibits coagulation (clotting) by inactivating at least two proteins, Factors V and VIII. When there is a deficiency of protein C, coagulation may take place lending to possible thrombosis.

Defects can occur for a wide variety of reasons in the clotting or anticlotting mechanisms,...

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