To reduce the development of drug-resistant bacteria and maintain the effectiveness of AMOXIL and other antibacterial drugs, AMOXIL should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy. Indicated surgical procedures should be performed. DOSAGE AND ADMINISTRATION Capsules, chewable tablets, and oral suspensions of AMOXIL may be given without regard to meals. The 400-mg suspension, 400-mg chewable tablet, and the 875-mg tablet have been studied only when administered at the start of a light meal. However, food effect studies have not been performed with the 200-mg and 500-mg formulations. Neonates and infants aged . 1 2 weeks ( . 3 months): Due to incompletely developed renal function affecting elimination of amoxicillin in this age group, the recommended upper dose of AMOXIL is 30 mg/ kg/ day divided q12h. Adults and pediatric patients >3 months Infection Severity * Usual Adult Dose Usual Dose for Children >3 months ** Ear/ nose/ throat Mild/ Moderate 500 mg every 12 hours or 250 mg every 8 hours 25 mg/ kg/ day in divided doses every 12 hours or 20 mg/ kg/ day in divided doses every 8 hours Infection Severity * Usual Adult Dose Usual Dose for Children >3 months ** Severe 875 mg every 12 hours or 500 mg every 8 hours 45 mg/ kg/ day in divided doses every 12 hours or 40 mg/ kg/ day in divided doses every 8 hours Lower respiratory tract Mild/ Moderate or Severe 875 mg every 12 hours or 500 mg every 8 hours 45 mg/ kg/ day in divided doses every 12 hours or 40 mg/ kg/ day in divided doses every 8 hours Mild/ Moderate 500 mg every 12 hours or 250 mg every 8 hours 25 mg/ kg/ day in divided doses every 12 hours or 20 mg/ kg/ day in divided doses every 8 hours | ||||
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