DESCRIPTION
Tamsulosin hydrochloride is an antagonist of alpha1A adrenoceptors in the prostate.
Tamsulosin HCl is (-)-( R)-5-[ 2-[[ 2-( 0-ethoxyphenoxy) ethyl] amino] propyl]-2-methoxybenzenesulfonamide, monohydrochloride. Tamsulosin HCl occurs as white crystals that melt with decomposition at approximately 230° C. It is sparingly soluble in water and in methanol, slightly soluble in glacial acetic acid and in ethanol, and practically insoluble in ether.
The empirical formula of tamsulosin HCl is C20H28N2O5S . HCl. The molecular weight of tamsulosin HCl is 444.98.
Each FLOMAX capsule for oral administration contains tamsulosin HCl 0.4 mg, and the following inactive ingredients: methacrylic acid copolymer, microcrystalline cellulose, triacetin, polysorbate 80, sodium lauryl sulfate, calcium stearate, talc, FD& C blue No. 2, titanium dioxide, ferric oxide, gelatin, and trace amounts of
