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Ultram - Indications & Dosage

[Tramadol]



° The recommended dose for adult patients with cirrhosis is 50 mg every 12 hours.

° In general, dose selection for an elderly patient over 65 years old should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal or cardiac function and of concomitant disease or other drug therapy. For elderly patients over 75 years old, total dose should not exceed 300 mg/ day.

HOW SUPPLIED

ULTRAM (tramadol hydrochloride tablets) Tablets Ð 50 mg (white, scored, film-coated capsule-shaped tablet) debossed "ULTRAM" on one side and "06 59" on the other side.
100's Ð NDC 0045-0659-60 bottles of 100 tablets
500's Ð NDC 0045-0659-70 bottles of 500 tablets
Packages of 100 unit doses in blister packs Ð NDC 0045-0659-10 (10 cards of 10 tablets each).

Dispense in a tight container. Store at 25° C (77° F); excursions permitted to 15 -30° C (59 -86° F).

OMP DIVISION ORTHO-McNEIL PHARMACEUTICAL, INC.
Raritan, New Jersey 08869
U. S. Patents 3,652,589 and 3,830,934 © OMP 2001 Revised August 2001 7517003

Up to Up to Up to 7 Days 30 Days 90 Days
Dizziness/ Vertigo 26% 31% 33% Nausea 24% 34% 40%
Constipation 24% 38% 46% Headache 18% 26% 32%
Somnolence 16% 23% 25% Vomiting 9% 13% 17%
Pruritus 8% 10% 11% "CNS Stimulation" 1 7% 11% 14%
Asthenia 6% 11% 12% Sweating 6% 7% 9%
Dyspepsia 5% 9% 13% Dry Mouth 5% 9% 10%
Diarrhea 5% 6% 10%
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