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Obesity hypoventilation syndrome (OHS)



Respiratory system
Respiratory system


Obesity hypoventilation syndrome (OHS)

Alternative Names:

Pickwickian syndrome
Symptoms:

The main symptoms of OHS are due to sleep deprivation, and include:

  • Excessive daytime sleepiness
  • Falling asleep at inappropriate times during the day
  • Increased risk for accidents or errors at work
  • Depression

Symptoms of chronic hypoxia (low blood oxygen level) can also occur, such as shortness of breath or fatigue after minimal physical effort.


Signs and tests:


Persons with OHS are usually extremely overweight. Physical signs that suggest OHS include:

  • Cyanosis (bluish coloration of the lips, fingers, toes, or skin)
  • Signs of right-side heart failure (cor pulmonale ) such as swollen legs or feet, shortness of breath, or feeling fatigued after little exertion.

Tests done to confirm the diagnosis include:

  • Sleep study
  • Pulmonary function
  • Arterial blood gas

The presence of high carbon dioxide (CO2) levels in the blood when a person is awake helps distinguish OHS from obstructive sleep apnea.


References:

Murray J, Nadel J. Textbook of Respiratory Medicine. 3rd ed. Philadelphia, Pa: W.B. Saunders Company; 2000:2326-2328.

Moore DP, Jefferson JW. Handbook of Medical Psychiatry. 2nd ed. St. Louis, Mo: Mosby, Inc; 2004:221-223.




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