Histoplasmosis - disseminated

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Disseminated histoplasmosis Fungus

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Histoplasmosis - disseminated

Disseminated histoplasmosis is an infection caused by inhaling the spores of the fungus Histoplasma capsulatum. This spore is found in moist soil areas along river valleys, such as the Mississippi and Ohio River Valleys.

Histoplasmosis is caused by a fungus found in the central and eastern U.S. Mississippi and Ohio River Valley, eastern Canada, Mexico, Central America, South America, Africa, and Southeast Asia.

Most cases are mild or without symptoms. Acute pulmonary histoplasmosis may occur in epidemics. Progressive or spreading (disseminated) and chronic disease can also occur. In disseminated disease, the infection has spread to other organs from the lungsthrough the bloodstream.

The liver and spleen are usually enlarged, and all body organsmay be involved. Ulcerations of the mouth or gastrointestinal tract may occur. Risk factors are travel to or residence within the central or eastern U.S., and exposure to the droppings of birds and bats.

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