Alpha-1 antitrypsin deficiency

Table of Contents

Alternative Names

AAT deficiency


Treatment

Treatment for AAT deficiency involves replacing the missing AAT protein. The protein is given through a vein each week. However, it is not yet known who may benefit from such therapy.

Quitting smoking is crucial.

Other treatments for emphysema and cirrhosis are also used.


Support Groups


Expectations (prognosis)

Some people with this deficiency will not develop liver or lung disease. However, emphysema and cirrhosis can be life threatening.


Complications
  • Bronchiectasis
  • Cirrhosis or liver failure
  • Emphysema
  • Liver cancer

Calling your health care provider

Call your health care provider if you develop symptoms of AAT deficiency.



Review Date: 09/15/2010
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of Pulmonary, Allergy and Critical Care, University of Pennsylvania, Philadelphia, PA. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)