Wegener?s granulomatosisFrom our partner site on prostate, ProstateCommons.com. Midline granulomatosis Symptoms: Frequent sinusitis is the most common symptom. Other early symptoms include persistent fever without an obvious cause,night sweats, fatigue, and malaise (an ill feeling). Chronic ear infectionsmay alsocome beforethe diagnosis of Wegener's granulomatosis. Other upper respiratory symptoms include nose bleeds, pain, and sores around the opening of the nose. advertisement Loss of appetite and weight loss are common. Skin lesions typically occur, but there is no onetypical lesion associated with the disease. Symptoms of kidney disease may be present (but not always). The urine may be bloody, and often first appears as red or smoky urine. Eye problems develop in a significant number of patients. Theymay range from mild conjunctivitis to severeswelling of the eye. Other symptoms include:
Signs and tests: A variety of tests may be performed, including:
References: Murray J, Nadel J. Textbook of Respiratory Medicine. 3rd ed. Philadelphia, Pa: W.B. Saunders Company; 2000: 1462-1463.
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