Peripheral artery disease is a condition of the blood vessels that leads to narrowing and
The narrowing of the blood vessels leads to decreased blood flow, which can injure nerves and other tissues.
Peripheral vascular disease; PVD; PAD; Arteriosclerosis obliterans; Blockage of leg arteries; Claudication; Intermittent claudication; Vaso-occlusive disease of the legs; Arterial insufficiency of the legs; Recurrent leg pain and cramping; Calf pain with exercise
Causes, incidence, and risk factors
Peripheral artery disease is caused by
As a result, when the muscles of your legs are working harder (such as during exercise or walking) they cannot get enough blood and oxygen. Eventually, there may not be enough blood and oxygen, even when the muscles are resting.
Peripheral artery disease is a common disorder that usually affects men over age 50. People are at higher risk if they have a history of:
- Abnormal cholesterol
- Heart disease (coronary artery disease)
- High blood pressure (
Kidney diseaseinvolving hemodialysis
- Stroke (
Review Date: 06/17/2010
Reviewed By: Shabir Bhimji, MD, PhD, Specializing in Cardiothoracic and Vascular Surgery, Midland, TX. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.