Thursday, February, 09, 2012

Beriberi

Table of Contents

Alternative Names

Thiamine deficiency; Vitamin B1 deficiency


Symptoms

Symptoms of dry beriberi include:

  • Difficulty walking
  • Loss of feeling (sensation) in hands and feet
  • Loss of muscle function or paralysis of the lower legs
  • Mental confusion/speech difficulties
  • Pain
  • Strange eye movements (nystagmus)
  • Tingling
  • Vomiting

Symptoms of wet beriberi include:

  • Awakening at night short of breath
  • Increased heart rate
  • Shortness of breath with activity
  • Swelling of the lower legs

Signs and tests

A physical examination may show signs of congestive heart failure, including:

  • Difficulty breathing with neck veins that stick out
  • Enlarged heart
  • Fluid in the lungs
  • Rapid heartbeat
  • Swelling in both lower legs

A person with late-stage beriberi may be confused or have memory loss and delusions. The person may be less able to sense vibrations.

A neurological exam may show signs of:

  • Changes in the walk
  • Coordination problems
  • Decreased reflexes
  • Drooping of the eyelids

The following tests may be done:

  • Blood tests to measure the amount of thiamine in the blood
  • Urine tests to see if thiamine is passing through the urine


Review Date: 07/22/2010
Reviewed By: Linda J. Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington, School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)