Pseudotumor cerebri

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Pseudotumor cerebri

Pseudotumor cerebri is a reversible process affecting the brain that appears to be -- but is not -- a tumor. The major symptom is increased pressure within the skull (increased intracranial pressure). There is no evidence of tumor, infection, blocked drainage of the fluid surrounding the brain, or any other cause.

The cause for the condition is unknown.

The following factors increase the risk:

• Obesity
• Non-steroidal anti-inflammatory drugs (NSAIDs), tetracycline, nitrofurantoin, isotretinoin, tamoxifen, naladixic acid, lithium, and the starting or stopping of steroids
• Vitamin A (too much or too little)
• Cushing?s disease
• Hypoparathyroidism
• Hypothyroidism
• Chronic renal failure
• Anemia

The condition occurs more frequently in women than men, particularly in pre-menopausal obese women. It is rare in infants.

The diagnosis is made when other health conditions are ruled out. Several conditions may cause increased intracranial pressure, including venous sinus thrombosis, hydrocephalus, an intracranial mass (such as a tumor), and Guillain-Barr syndrome.

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