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Eosinophilic fasciitis



Superficial anterior muscles
Superficial anterior muscles


Eosinophilic fasciitis

Definition:

Eosinophilic fasciitis is a syndrome in which muscletissue underneath the skin, called fascia,becomes inflammedandthickens.Rapid swelling can occurin the hands, arms, legs, and feet. The diseaseis similar to scleroderma.


Causes, incidence, and risk factors:


The cause of eosinophilic fasciitis is unknown. There is agathering of eosinophils, a type of white blood cell, into the affected fascia and muscles. Eosinophils are associated with allergic-type reactions, but their specific function is largely unknown.

The syndrome is most common in people between ages 30 and 60. In some cases, itappears to beprecipitated by strenuous physical activity.


References:

Harris ED. Budd RC, Genovese MC, Firestein GS, Sargent JS, Sledge CB. Kelley's Textbook of Rheumatology. 7th ed. St Louis, MO: WB Saunders;2005:1302-1303.




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