Analgesic nephropathy

Injury	Disease	Nutrition	Poison

Symptoms	Surgery	Test	Special Topic

Male urinary system

Analgesic nephropathy

Alternative Names:

Phenacetin nephritis; Nephropathy - analgesic
Symptoms:

Weakness
Fatigue
Increased urinary frequency or urgency
Blood in the urine
Flank pain or back pain, renal colic (occasional)
Decreased urine output
Decreased alertness
Decreased sensation, numbness (especially of extremities)
Nausea, vomiting
Easy bruising or bleeding
Swelling, generalized

Note: There may be no symptoms.
Signs and tests:

An examination may be unrevealing but may indicate interstitial nephritis or renal failure.Blood pressure may be elevated. There may be signs of fluid overload, including abnormal heart or lung sounds. Premature skin aging may be evident.

A blood toxicology screen may be positive for salicylate.
A urinalysis shows blood and white cells.
A CBC may show anemia, with decreased number of red blood cells.
A histology (examination) of sediment or tissue passed in the urine may show necrotic (dead) papillary tissue.
An IVP (intravenous pyelogram ) may show papillary necrosis (tissue death) or sloughed papillae in the renal pelvis or ureter.