Glomerulonephritis is a type of kidney disease in which the part of your kidneys that helps filter waste and fluids from the blood is damaged.

Glomerulonephritis - chronic; Chronic nephritis; Glomerular disease; Necrotizing glomerulonephritis; Glomerulonephritis - crescentic; Crescentic glomerulonephritis; Rapidly progressive glomerulonephritis

Glomerulonephritis may be caused by specific problems with the body's immune system. Often, the precise cause of glomerulonephritis is unknown.

Damage to the glomeruli causes blood and protein to be lost in the urine.

The condition may develop quickly, with loss of kidney function occurring over weeks and months (called rapidly progressive glomerulonephritis).

In about a quarter of people with chronic glomerulonephritis there is no history of kidney disease and the disorder first appears as chronic renal failure.

The following increase your risk of developing this condition:

• History of cancer
• Blood or lymphatic system disorders
• Exposure to hydrocarbon solvents
• Infections such as strep infections, viruses, heart infections,or abscesses
• Diabetes

Many conditions are known to cause or increase the risk for glomerulonephritis, including:

• Focal segmental glomerulosclerosis
• Goodpasture syndrome
• Membranoproliferative GN
• IgA nephropathy
• Lupus nephritis or Henoch-Schonlein purpura
• Anti-glomerular basement membrane antibody disease
• Blood vessel diseases such as vasculitis or polyarteritis
• Amyloidosis

Images

Kidney anatomy

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Glomerulonephritis Symptoms

Review Date: 08/12/2009
Reviewed By: Parul Patel, MD, Private Practice specializing in Nephrology and Kidney and Pancreas Transplantation, California Pacific Medical Center, San Francisco, CA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)