Proximal renal tubular acidosis

Table of Contents

Alternative Names

Renal tubular acidosis - proximal; Type II RTA; RTA - proximal; Renal tubular acidosis type II


Symptoms
  • Confusion or decreased alertness
  • Dehydration
  • Fatigue
  • Increased breathing rate
  • Osteomalacia
  • Muscle pain
  • Rickets
  • Weakness

Other symptoms can include:

  • Decreased urine output
  • Increased heart rate or irregular heartbeat
  • Muscle cramps
  • Pain in the bones, back, flank, or abdomen
  • Skeletal deformities

Signs and tests

Arterial blood gas and blood chemistries may suggest metabolic acidosis and electrolyte imbalances, most often low levels of potassium or bicarbonate.

Other tests that may be done include:

  • Blood pH level
  • Urine pH
  • Urinalysis may show abnormal levels of phosphate, calcium, glucose, and amino acids

This disease may also change the results of the following tests:

  • Acid loading test (pH)
  • Blood potassium level
  • Urine calcium
  • Urine citric acid
  • Urine potassium level


Review Date: 11/30/2009
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Herbert Y. Lin, MD, PHD, Nephrologist, Massachusetts General Hospital; Associate Professor of Medicine, Harvard Medical School. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)