Table of Contents
- Overview
- Symptoms
- Treatment
- Prevention
- Images
Christmas disease; Factor IX hemophilia
Symptoms
The severity of symptoms can vary, and the severe forms become apparent early on.
Bleeding is the main symptom of the disease and sometimes, although not always, occurs if an infant is circumcised. Additional bleeding problems usually show up when the infant becomes mobile.
Mild cases may go unnoticed until later in life, when they occur in response to surgery or trauma. Internal bleeding may occur anywhere and bleeding into joints is common.
Symptoms can include:
- Bleeding into joints and associated pain and swelling
-
Blood in the urine or stool Bruising - Excessive bleeding following circumcision
- Gastrointestinal tract and urinary tract hemorrhage
Nosebleeds - Prolonged bleeding from cuts, tooth extraction, and surgery
- Spontaneous
bleeding
Signs and tests
If the patient is the first person in the family to have a suspected bleeding disorder, he or she will undergo a series of tests called a coagulation study. Once the specific defect has been identified, other family members will need less testing to diagnose the disorder.
Tests results may include:
- Prolonged
partial thromboplastin time (PTT) - Normal
prothrombin time - Normal
bleeding time - Normal
fibrinogen level - Low
factor IX
Images
Previous Section
Review Date: 03/28/2010
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of
General Medicine, Department of Medicine, University of Washington
School of Medicine; James R. Mason, MD, Oncologist, Director, Blood
and Marrow Transplantation Program and Stem Cell Processing Lab,
Scripps Clinic, Torrey Pines, California. 3/28/10Also reviewed by
David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)
