Lupus anticoagulants are antibodies against substances in the lining of cells that prevent blood clotting in a test tube. These substances are called phospholipids.
Persons with these antibodies may have an abnormally high risk of blood clotting.
Causes, incidence, and risk factors
Lupus anticoagulants are usually found in persons with autoimmune diseases, such as
They may also be found in persons who take certain medications, including phenothiazines, phenytoin, hydralazine, quinine, and the antibiotic amoxicillin.
Persons with inflammatory bowel disease (
Some people have no risk factors for this condition. In some cases, SLE is linked to an increased risk of
Review Date: 01/24/2011
Reviewed By: Todd Gersten, M.D., Hematology/Oncology, Palm Beach Cancer Institute, West Palm Beach, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.