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Thrombotic thrombocytopenic purpura

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Blood cells

Thrombotic thrombocytopenic purpura

Alternative Names:

TTP
Symptoms:

Fever
Weakness
Easy fatigue
Pallor
Shortness of breath on exertion
Heart rate over 100 per minute
Purpura -- purplish discolorations in the skin produced by small bleeding vessels near the surface of the skin
Bleeding into the skin or mucus membranes
Headache
Confusion
Speech changes
Alterations in consciousness
Yellowish color to the skin (jaundice)

Signs and tests:

Platelet count is low
CBC shows anemia
Bilirubin is high
Blood smear shows schistocytes and fragmented blood cells
Urinalysis shows protein or microscopic blood particles
Creatinine level is high
Mucus membrane biopsy reveals platelet clots in small blood vessels

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