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Granuloma inguinale



Skin layers
Skin layers


Granuloma inguinale

Alternative Names:

Donovanosis
Treatment:

A complete cure of granuloma inguinale requires fairly long treatment. Most treatment courses run 3 weeks or until the lesions have completely healed. The antibiotics used include:

  • Tetracycline or doxycycline
  • Sulfamethoxazole
  • Gentamicin
  • Streptomycin
  • Ciprofloxacin
  • Erythromycin
A follow-up examination is essential because the disease can reappear after an apparently successful cure.
Expectations (prognosis):


Treating this disease early decreases the chances of tissue destruction or scarring. Untreated disease can lead to complications.


Complications:
  • Genital destruction and scarring
  • Genital depigmentation (loss of skin color)
  • Permanent genital swelling from lymphatic scarring

Calling your health care provider:

Call for an appointment with your health care provider if you have had sexual exposure to a person who is known to have granuloma inguinale, or if you develop symptoms similar to those listed above.


References:

Keck JW.Ulcerative Lesions. Clin Fam Pract. 2005 Mar; 7(1); 13-30.

Rackel RE, Bope ET. Granuloma Inguinale. In: Conn's Current Therapy 2005. 57th ed. St. Louis, MO: Saunders; 2005:859.




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