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CMV - gastroenteritis/colitis



Gastrointestinal anatomy
Gastrointestinal anatomy
Stomach and stomach lining
Stomach and stomach lining


CMV - gastroenteritis/colitis

Alternative Names:

Colitis - cytomegalovirus; Gastroenteritis - cytomegalovirus; Esophagitis - cytomegalovirus; Gastrointestinal CMV disease
Treatment:

The goals of therapy are to control the infection and relieve symptoms. Antiviral medications that may be used include ganciclovir (Cytovene) and foscarnet (Foscavir). Treatment is given intravenously (into a vein) and sometimes orally for several weeks.



In some cases, therapy may be prolonged. CMV hyperimmune globulin may be used in cases of severe refractory infection (when other drugs don't work). Antidiarrheal medications and analgesics (pain killers)are used for the relief of symptoms.

Nutritional supplements or intravenous nutrition (putting nutrients directly into the blood stream) may be used to combat wasting.


Expectations (prognosis):

In peoplewith normal immune systems,symptoms usually go awaywithout treatment.In those with suppressed immune systems, symptoms are more severe. The outcome depends upon the severity of the immunodeficiency and the severity of the infection.

People with AIDS may have a worse outcome than those with a different type of immunodeficiency. CMV infection typicallyaffects the entire body, even if patients only have GI symptoms. Therefore, overall outcome depends on the response totherapy with antiviral drugs.


Complications:

Low white blood cell count may occur with use of ganciclovir. Kidney problems may occur with the use of foscarnet.


Calling your health care provider:

Call for an appointment with your health care provider if symptoms develop that are suggestive of CMV gastroenteritis.




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