Senile cerebral amyloid angiopathy

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Amyloidosis on the fingers Arteries of the brain

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Senile cerebral amyloid angiopathy

Senile cerebral amyloid angiopathy is characterized by deposits of amyloid protein in the walls of the arteries of the brain, which increases the risk of bleeding into the brain (hemorrhagic stroke).

Senile cerebral amyloid angiopathy is a cause of lobar intracerebral hemorrhage (bleeding in a localized area of the brain, a form of stroke) in the elderly. There may be multiple episodes of bleeding, which may occur over a period of many months. The symptoms occur because bleeding in the brain harms brain tissue.

The cause is unknown. Amyloid protein is deposited in the arterial walls of the brain, and there are often no deposits elsewhere in the body. The major risk factor is age. The incidence is much greater in people older than 60.

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