Friday, February, 10, 2012

General paresis

Table of Contents

Symptoms
  • Decreased language ability (aphasia)
  • Decreased motivation
  • Impaired judgment
  • Loss of ability to calculate
  • Loss of long-term memory (long-past events)
  • Loss of short-term memory (recent events)
  • Muscle weakness (difficulty using legs, arms, or other parts of the body)
  • Personality changes
    • Delusions, hallucinations
    • Irritability, anger
    • Inappropriate moods
    • Low mood
  • Seizures

Signs and tests

Signs include:

  • Change in the response of the pupil in the eye
  • Irregular shape of the pupil
  • Inability to stand with the eyes closed (Romberg test)
  • Loss of sense of vibration and position
  • Muscle weakness
  • Problems with walking (gait)
  • Slowly worsening dementia, with loss of many brain functions

The doctor may do the following tests:

  • Eye exam
  • Muscle exam
  • Nervous system (neurologic) exam

Blood and urine tests to detect syphilis in the body include:

  • FTA-ABS
  • RPR
  • VDRL

Tests of the nervous system may include:

  • Cerebrospinal fluid (CSF)
  • Head CT scan and MRI
  • Nerve conduction tests


Review Date: 03/09/2010
Reviewed By: Linda J. Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington, School of Medicine; Daniel B. Hoch, PhD, MD, Assistant Professor of Neurology, Harvard Medical School, Department of Neurology, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)