Central pontine myelinolysis is brain cell dysfunction caused by the destruction of the layer (
Osmotic demyelination syndrome
Causes, incidence, and risk factors
The destruction of the myelin sheath that covers nerve cells prevents signals from being properly transmitted in the nerve. This decreases the nerve's ability to communicate with other cells.
The most common cause of central pontine myelinolysis is a quick rise in the body's sodium levels. This most often occurs when someone is being treated for low blood levels of sodium (
This condition does not occur on its own. It is a complication of treatment for other conditions or from the other conditions themselves.
- Liver disease
Malnutritionfrom serious illnesses
Review Date: 08/27/2010
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Daniel B. Hoch, PhD, MD, Assistant Professor of Neurology, Harvard Medical School, Department of Neurology, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.