Antifungal drugs, such as amphotericin B, itraconazole, and ketoconazole, are the usual treatments. Antifungals may be given intravenously depending on the form or stage of disease. In some cases, long-term treatment with antifungal drugs may be needed.

The outlook depends on the form of histoplasmosis and the condition of the individual's immune system. Death can occur in some cases.

• Bacterial skin infection
• Complications of medications (for example, amphotericin B can have severe, unpleasant side effects)

The skin lesions may be similar to skin problems from other infections or illnesses. Notify your health care provider if you develop any suspicious lesions on your skin, so that you may be tested correctly.

Images

Histoplasmosis, disseminated in HIV patient

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Review Date: 09/15/2010
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Jatin M. Vyas, MD, PhD, Instructor in Medicine, Harvard Medical School, Assistant in Medicine, Division of Infectious Disease, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)