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Bullous pemphigoid


From our partner site on skin cancer, SkinCancerConnection.com.

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Bullous pemphigoid, close-up of tense blisters
Bullous pemphigoid, close-up of tense blisters
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Bullous pemphigoid

Symptoms:

  • Bullae (large blisters, thin-walled sacs filled with clear fluid, greater than 1 cm diameter)
    • Multiple
    • Usually located on the arms, legs, or trunk
    • May also occur in the mouth
    • May weep, crust over
    • May appear deep below the surface of the skin
    • May erode the skin, form ulcers or open sores
  • Itching
  • Rashes
  • Mouth sores
  • Bleeding gums

Signs and tests:

A skin lesion biopsy shows a characteristic blistering pattern. A special type of skin biopsy may also be performed and examined by direct immunofluorescence. Some physicians may additionally order blood tests to help confirm the diagnosis.
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