MastoiditisFrom our partner site on diet & exercise, MyDietExercise.com. Mastoiditis may be difficult to treat because it is difficult for medications to reach deep enough into the mastoid bone. It may require repeated or long-term treatment. Antibiotics by injection, then antibiotics by mouth are given to treat the infection. advertisement Surgery to remove part of the bone and drain the mastoid (mastoidectomy) may be needed if antibiotic therapy is not successful. Surgical drainage of the middle ear through the eardrum (myringotomy) may be needed to treat the underlying middle ear infection. Expectations (prognosis): Mastoiditis is curable with treatment but may be hard to treat and may recur. Complications:
Calling your health care provider: Call your health care provider if symptoms indicate mastoiditis. Call for an appointment with your health care provider if a known ear infection does not respond to treatment or is followed by new symptoms, or if symptoms do not respond to treatment.
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