Hairy leukoplakia; Smoker's keratosis

The most common symptoms of hairy leukoplakia are painless, fuzzy white patches on the side of the tongue.

The skin lesions tend to have the following characteristics:

• Location
  • Usually on the tongue
  • May be on the inside of the cheeks
  • In females, occasionally on the genitals
• Color
  • Usually white or gray
  • May be red (called erythroplakia, a condition that can lead to cancer)
• Texture
  • Thick
  • Slightly raised
  • Hardened surface

The typical white patch of leukoplakia develops slowly, over weeks to months. The lesion may eventually become rough in texture, and may become sensitive to touch, heat, spicy foods, or other irritation.

A biopsy of the lesion confirms the diagnosis. An examination of the biopsy specimen may find changes that indicate oral cancer.

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Leukoplakia Overview

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Leukoplakia Treatment

Review Date: 08/28/2009
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School, Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)