Table of Contents
- Overview
- Symptoms
- Treatment
- Prevention
- Images
Glucuronyl transferase deficiency (type I Crigler-Najjar); Arias syndrome (type II Crigler-Najjar)
Symptoms
-
Confusion and changes in thinking - Yellow skin (jaundice) and yellow in the whites of the eyes (icterus), which begin a few days after birth and get worse over time
Signs and tests
Tests used to evaluate liver function include:
- Conjugated (bound) bilirubin
-
Liver biopsy ,enzyme assay - Total bilirubin level
- Unconjugated (unbound) bilirubin in blood
Images
Liver anatomy
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Crigler Treatment
Review Date: 09/10/2010
Reviewed By: Chad Haldeman-Englert, MD, Division of Human Genetics, Children's
Hospital of Philadelphia, Philadelphia, PA. Review provided by
VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA,
Medical Director, A.D.A.M., Inc.
A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)
