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Metabolic neuropathies



Central nervous system
Central nervous system


Metabolic neuropathies

Definition:

A metabolic neuropathy is a disease of the nerves caused by a problem regulating chemical processes in the body. In some cases, nerve damage is caused by the inability to properly use energy in the body. In other cases, various toxins accumulate and damage nerves. Some metabolic disorders are inherited, while others are acquired during life through various diseases.


Causes, incidence, and risk factors:


Diabetes is one of the most common metabolic neuropathies. Those who have poorly controlled blood sugar are at the highest risk. People who have damage to the kidneys or eyes from diabetes are also more likely to have nerve damage from diabetes.

Other common metabolic causes of neuropathies include:

  • Thyroid disease
  • Hypoglycemia (low blood sugar)
  • Nutritional deficiencies, including vitamin B12, vitamin B6, vitamin E, and vitamin B1 deficiency
  • Alcoholism
  • Sepsis (severe systemic infection)
  • Kidney failure
  • Porphyria



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