Hyperkalemia

If kidney function is adequate, and sufficient amounts of aldosterone are present, tissue trauma alone rarely results in hyperkalemia. A normally functioning kidney will excrete the excess potassium that has been released from the cells.

Increased intake of potassium may cause hyperkalemia if kidney function is poor. Salt substitutes often contain potassium, as do many "low-salt" packaged foods. Hyperkalemia may be caused by medications, including medications that affect kidney function (potassium sparing diuretics, such as spironolactone, amiloride, or triamterene) and potassium supplements (especially intravenous potassium).

Hyperkalemia can have serious, potentially life-threatening effects on the body. A gradual increase in potassium, as may occur with chronic renal failure, may be better tolerated than a sudden increase. Slightly higher than normal potassium levels may be well tolerated by some persons with chronic renal failure.

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