Table of Contents
- Overview
- Symptoms
- Treatment
- Prevention
- Images
CGD; Fatal granulomatosis of childhood; Chronic granulomatous disease of childhood; Progressive septic granulomatosis
Symptoms
- Bone infections
- Frequent and difficult-to-clear skin infections
- Abscesses
- Chronic infection inside the nose
- Furuncles
- Impetiginized
eczema (eczema complicated by an infection) - Impetigo
- Perianal abscesses (abscesses around the anus)
- Joint infections
- Persistent diarrhea
- Pneumonia
- Occurs frequently
- Difficult to cure
-
Swollen lymph nodes in the neck; those develop early in life, and stay swollen or occur frequently. The lymph nodes may form abscesses that require surgical drainage.
Signs and tests
A tissue biopsy may show granulomas (groups of abnormal phagocytes).
Other tests may include:
Bone scan Chest x-ray -
Complete blood count (CBC) - Flow cytometry tests
-
Nitroblue tetrazolium test (NBT) to confirm the disease and detect that the mother is a carrier
Images
Previous Section
Review Date: 09/15/2010
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of
General Medicine, Department of Medicine, University of Washington
School of Medicine; Jatin M. Vyas, MD, PhD, Instructor in Medicine,
Harvard Medical School, Assistant in Medicine, Division of
Infectious Disease, Massachusetts General Hospital. Also reviewed
by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)
