CGD; Fatal granulomatosis of childhood; Chronic granulomatous disease of childhood; Progressive septic granulomatosis

Acute infections should be treated aggressively with appropriate antibiotics. Antibiotics may also be prescribed to prevent infection (prophylactically). These are taken on a daily basis to try to decrease the frequency of infection. Interferon-gamma may also be helpful in reducing the number of severe infections. When abscesses form, if possible they should be treated by a surgeon

The only cure for chronic granulomatous disease is a bone marrow transplant.

Long-term antibiotic treatments may help to reduce infections, but early death is typically a result of repeated lung infections.

• Bone damage
• Chronic pneumonia
• Lung damage
• Skin damage

If you or your child have this condition and you suspect pneumonia or other infection, call your health care provider immediately.

Notify your health care provider if a lung, skin, or other infection does not respond to treatment.

Images

Antibodies

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Chronic granulomatous disease Symptoms

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Chronic granulomatous disease Prevention

Review Date: 09/15/2010
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Jatin M. Vyas, MD, PhD, Instructor in Medicine, Harvard Medical School, Assistant in Medicine, Division of Infectious Disease, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)