Glanzmann’s disease is a rare disorder of blood platelets, which results in easy bruising and nosebleeds.

Thrombasthenia

Glanzmann's disease is caused by the lack of a protein that is normally on the surface of platelets, which is needed for them to clump together (aggregate) normally.

The condition is congenital, which means it is present from birth. There are several genetic abnormalities that can cause the condition.

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Glanzmann’s disease Symptoms

Review Date: 02/28/2011
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)