Table of Contents
- Overview
- Symptoms
- Treatment
- Prevention
- Images
Bruton's agammaglobulinemia; X-linked agammaglobulinemia
Symptoms
Symptoms include frequent episodes of:
Bronchitis - Chronic
diarrhea -
Conjunctivitis (eye infection) -
Otitis media (middle ear infection) Pneumonia Sinusitis - Skin infections
- Upper respiratory tract infections
Infections typically appear in the first 4 years of life.
Other symptoms include:
-
Bronchiectasis (a disease in which the small air sacs in the lungs become damaged and enlarged) - Unexplained
asthma
Signs and tests
The disorder is confirmed by laboratory measurement of blood immunoglobulins.
Tests include:
- Flow cytometry to measure circulating B lymphocytes
Immunoelectrophoresis - serum -
Quantitative immunoglobulins - IgG, IgA, IgM (usually measured by nephelometry)
Images
Previous Section
Review Date: 05/16/2010
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of
General Medicine, Department of Medicine, University of Washington
School of Medicine; and Stuart I. Henochowicz, MD, FACP, Associate
CLinical Professor of Medicine, Division of Allergy, Immunology,
and Rheumatology, Georgetown University Medical School. Also
reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)
