Anthrax

Injury	Disease	Nutrition	Poison

Symptoms	Surgery	Test	Special Topic

Cutaneous anthrax

Anthrax

Definition:

Anthrax is an infectious disease caused by the spore-forming bacteria called Bacillus anthracis. Infection in humans most often involves the skin, the gastrointestinal tract, or the lungs.

Alternative Names:

Wool sorter's disease; Ragpicker's disease

Causes, incidence, and risk factors:

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Anthrax commonly affects hoofed animals such as sheep and goats, but humanswho come in contact with the infected animals canget sick from anthrax, too. Historically, the populations most at risk for anthrax included farm workers, veterinarians, and tannery and wool workers.

There are three primary routes of anthrax infection:

Cutaneous anthraxoccurs when anthraxtouches a cut or scrape on the skin.
Inhalation anthrax develops when anthrax spores enter the lungs.
Gastrointestinalanthraxoccurs when someone eats anthrax-contaminated meat. The disease usually develops within one week, and can affect themouth,esophagus,intestines, and colon. The infectioncan spread tothe bloodstream, and may result in death.

Anthrax is a potential agent for use as a biological weapon or for bio-terrorism. In 2001, bioterrorist activities involving the U.S. Postal Service infected22 people with anthrax; 7 survivors had confirmed cutaneous anthrax disease.

While at least 17 nations are believed to have a biological weapons program, it is unknown how many nations or groups are working with anthrax. Most bio-terrorism experts have concluded that it is technologically difficult to use anthrax effectively as a weapon on a large scale.

References:

Reissman DB, Whitney EA, Taylor TH Jr, et al. One-Year Health Assessment of Adult Survivors of Bacillus anthracis Infection.JAMA. 2004;291:1994-1998.

Inglesby TV, O'Toole T, Henderson DA, et al. Anthrax as a Biological Weapon, 2002. JAMA.160;2002;287:2236-2252.