Rabies

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Rabies

Central nervous system

Rabies

Definition:

Rabies is a frequently fatal, acute viral infection. You can get rabies when aninfected animal (often racoons, dogs, or bats)bites you or whenthe infected animal's saliva touches a scrape or cut on your skin. Rabies may also bespread from person to person through organ transplantation.

Causes, incidence, and risk factors:

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Rabies isspread by infected saliva that enters the body through a bite or broken skin. The virus travels from the wound to the brain, where it causes swelling, called inflammation.This inflammationresults in the symptoms of the disease.

The actual time between infection and when you get sick (called the "incubation period") ranges from 10 days to 7 years. The average incubation period is 3 to 7 weeks.

In the past, human cases in the U.S. usually resulted from a dog bite, but recently, more cases of human rabies have been linked to racoons or bats. Although dog bites are a common cause of rabies in developing countries, there have been no reports ofrabiescaused by dog bites in the U.S. for a number of years due to widespread animal vaccination.

Besides dogs, bats, skunks, raccoons, foxes, and other wild animals can also be sources of the rabies virus. There are an estimated 55,000 deaths from rabies worldwide each year. Most deaths occurin children.

The United Kingdom had once completely eradicated rabies. This is no longer true. Recently, rabies-infected bats have been found in Scotland.

References:

Marx J. Rosen?s Emergency Medicine: Concepts and Clinical Practice. 5th ed. St. Louis, Mo: Mosby; 2002:1837-1838.

Stantic-Pavlinic M. Public health concerns in bat rabies across Europe. Euro Surveill. 2005 Nov 1;10(11) .

Brookes SM, Aegerter JN, Smith GC. European bat lyssavirus in Scottish bats. Emerg Infect Dis. 2005 Apr;11(4):572-8.

Cohen J, Powderly WG. Infectious Diseases. 2nd ed. New York, NY: Elsevier; 2004:1503-1506.