Neuroblastoma is a malignant (cancerous)
Causes, incidence, and risk factors
Neuroblastoma can occur in many areas of the body. It develops from the tissues that form the sympathetic nervous system (the part of the nervous system that controls body functions, such as
Most neuroblastomas begin in the abdomen in the adrenal gland or next to the spinal cord, or in the chest. They may also start in other areas. Neuroblastomas can spread to the bones (face, skull, pelvis, shoulders, arms, and legs), bone marrow, liver, lymph nodes, skin, and around the eyes (orbits).
The cause of the tumor is unknown. Neuroblastoma is most commonly diagnosed in children before age 5. The disorder occurs in approximately 1 out of 100,000 children and is slightly more common in boys.
In most patients, the neuroblastoma has already spread when it is first diagnosed.
Review Date: 12/28/2010
Reviewed By: Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program,
Massachusetts General Hospital. Also reviewed by David Zieve, MD,
MHA, Medical Director, A.D.A.M., Inc.
A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)
