Quincke's disease

• Airway blockage -- involves throat swelling and sudden hoarseness
• Repeat episodes of abdominal cramping without obvious cause
• Swelling in the arms, legs, lips, eyes, tongue, or throat
• Swelling of the intestines -- can be severe and lead to abdominal cramping, vomiting, dehydration, diarrhea, pain, and occasionally shock

There is usually no itching or hives.

Blood tests (ideally done during an episode):

• C1 inhibitor function
• C1 inhibitor level
• Complement components C4 and C2

Images

Antibodies

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Hereditary angioedema Overview

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Hereditary angioedema Treatment

Review Date: 05/09/2010
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Stuart I. Henochowicz, MD, FACP, Associate Clinical Professor of Medicine, Division of Allergy, Immunology, and Rheumatology, Georgetown University Medical School. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)