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Multiple lentigines syndrome


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Multiple lentigines syndrome

Alternative Names:

Leopard syndrome
Symptoms:
  • Afamily history of multiple lentigines
  • Multiple lentigines on neck and trunk (may be on any cutaneous surface)
  • Cafe-au-lait spots
  • Wide-set eyes (hypertelorism)
  • Prominent ears
  • Pectus excavatum
  • Pectus carinatum (abnormalities of the sternum or breastbone)
  • Undescended testicles (cryptorchidism)
  • Slow growth
  • Delayed puberty
  • Absent puberty

Signs and tests:
text continues below

A physical examination may show signs of mild pulmonic stenosis (obstruction of the pulmonic heart valve) and obstructive cardiomyopathy.

Tests:
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