Table of Contents
- Overview
- Symptoms
- Treatment
- Prevention
- Images
IgA deficiency
Treatment
No specific treatment is available. Some people gradually develop normal levels of IgA without treatment.
Infections should be treated with antibiotics. In some cases, longer courses of antibiotics may be needed to prevent infections from coming back.
Those with selective IgA deficiency who also have IgG subclass deficiencies can benefit from immunoglobulin (IVIG) treatments given through a vein.
Autoimmune disease treatment is based on the specific problem.
Note: People with complete IgA deficiency may develop anti-IgA antibodies if given blood products and IVIG. This may lead to
Support Groups
Expectations (prognosis)
Selective IgA deficiency is less harmful than many other immunodeficiency diseases.
Some people with IgA deficiency will recover on their own and begin to produce IgA in larger quantities over a period of years.
Complications
An autoimmune disorder such as
Patients with IgA deficiency may develop antibodies to IgA, and can have severe, even life-threatening reactions to transfusions of blood and blood products. If transfusions are necessary, washed cells may be cautiously given.
Calling your health care provider
Consider genetic counseling if you have a family history of selective IgA deficiency and you plan to have children.
If you have an IgA deficiency, be sure to mention it to your health care provider if IVIG or other blood-component transfusions are suggested as a treatment for any condition.
Images
Review Date: 05/16/2010
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of
General Medicine, Department of Medicine, University of Washington
School of Medicine; and Stuart I. Henochowicz, MD, FACP, Associate
Clinical Professor of Medicine, Division of Allergy, Immunology,
and Rheumatology, Georgetown University Medical School. Also
reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)
