Luteal phase defect

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Luteal phase defect

Luteal phase defect is when there is inadequate secretion or action of the hormone progesterone during the menstrual cycle. This results in a lag of more than two days in the development of the endometrium (the lining of the uterus, where an egg implants).

Inadequate luteal phase

The concept of luteal phase defect is controversial, and its role in infertility is uncertain. It may affect about 3 to 4% of infertile women, and up to 5% in women with a history of recurrent, spontaneous abortions. However, luteal phase defect can be found in up to 30% of isolated cycles of normal women.

Risks factors include:

• A history of unexplained infertility
• A history of recurrent spontaneous abortions

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