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Congenital rubella



Slit-lamp exam
Slit-lamp exam
Rubella on an infant's back
Rubella on an infant's back
Rubella Syndrome
Rubella Syndrome


Congenital rubella

Symptoms:

  • History of mother having rubella while pregnant (particularly in the first trimester)
  • Skin rash at birth (purpura, petechiae)
  • Low birth weight
  • Small head size (microcephaly)
  • Lethargy
  • Irritability
  • Deafness
  • Seizures
  • Cloudy corneas or white appearance to pupil (leukocoria)
  • Developmental delay
  • Mental retardation

Signs and tests:

Tests include:

  • Urine tests, nasopharyngeal secretions tests, or cerebrospinal fluid tests for virus
  • Antibody tests

References:


Edlich RF, Winters KL, Long WB 3rd, Gubler KD. Rubella and congenital rubella (German measles). J Long Term Eff Med Implants. 2005;15(3):319-28.

Bar-Oz B, Levichek Z, Moretti ME, Mah C, Andreou S, Koren G. Pregnancy outcome following rubella vaccination: a prospective controlled study. Am J Med Genet A. 2004 Sep 15;130(1):52-4.

Robertson SE, Featherstone DA, Gacic-Dobo M, Hersh BS. Rubella and congenital rubella syndrome: global update. Rev Panam Salud Publica. 2003 Nov;14(5):306-15. Review.




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