Saturday, February, 11, 2012

Bone marrow transplant

Table of Contents

Alternative Names

Transplant - bone marrow; Stem cell transplant; Hematopoietic stem cell transplant; Reduced intensity, nonmyeloablative transplant; Mini transplant; Allogenic bone marrow transplant; Autologous bone marrow transplant; Umbilical cord blood transplant


Risks

A bone marrow transplant may cause the following symptoms:

  • Pain
  • Chills
  • Fever
  • Hives
  • Chest pain
  • Drop in blood pressure
  • Shortness of breath
  • Nausea
  • Flushing
  • Headache
  • Funny taste in the mouth

Possible complications of a bone marrow transplant depend on many things, including:

  • The disease you are being treated for
  • If you had chemotherapy or radiation before the bone marrow transplant
  • Your age
  • Your overall health
  • How good of a match your donor was
  • The type of bone marrow transplant you received (autologous, allogeneic, or umbilical cord blood)

Complications can include:

  • Infections, which can be very serious
  • Bleeding in the lungs, the intestines, brain, and other areas of the body
  • Anemia
  • Stomach problems, including diarrhea, nausea, and vomiting
  • Pain
  • Inflammation and sorenes in the mouth, throat, esophagus, and stomach, called mucositis
  • Damage to the kidneys, liver, lungs, and heart
  • Cataracts
  • Early menopause
  • Graft failure, which means that the new cells do not settle into the body and start producing stem cells
  • Graft-versus-host disease , a condition in which the donor cells attack your own body
  • Delayed growth in children who receive a bone marrow transplant


Review Date: 03/17/2011
Reviewed By: Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)