Epicanthal folds

An epicanthal fold is skin of the upper eyelid -- from the nose to the inner side of the eyebrow -- that covers the inner corner (canthus) of the eye.

Plica palpebronasalis

The presence of an epicanthal fold is normal in people of Asiatic descent. An epicanthal fold is also common in children with Down syndrome. Epicanthal folds may also be seen in young children of any race before the bridge of the nose begins to elevate.

Epicanthal folds may be normal for people of Asiatic descent and some non-Asian infants. However, it may also be due to certain medical conditions, including:

• Down syndrome
• Fetal alcohol syndrome
• Turner syndrome
• Phenylketonuria (PKU)
• Williams syndrome
• Noonan syndrome
• Rubinstein-Taybi syndrome
• Blepharophimosis syndrome