C-reactive protein is produced by the liver. The level of CRP rises when there is inflammation throughout the body.

This article discusses the blood test done to measure the amount of CRP in your blood.

CRP; High-sensitivity C-reactive protein; hs-CRP

Blood is typically drawn from a vein, usually from the inside of the elbow or the back of the hand. The site is cleaned with germ-killing medicine (antiseptic). The health care provider wraps an elastic band around the upper arm to apply pressure to the area and make the vein swell with blood.

Next, the health care provider gently inserts a needle into the vein. The blood collects into an airtight vial or tube attached to the needle. The elastic band is removed from your arm.

Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.

In infants or young children, a sharp tool called a lancet may be used to puncture the skin and make it bleed. The blood collects into a small glass tube called a pipette, or onto a slide or test strip. A bandage may be placed over the area if there is any bleeding.

At the laboratory, your blood sample is mixed with a liquid called an antiserum, which contains substances that look for the specific protein.

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Review Date: 02/10/2011
Reviewed By: Michael E. Makover, MD, professor and attendingin Rheumatology and the New York University Medical Center, New York, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)