CSF chemistryFrom our partner site on chronic pain, ChronicPainConnection.com. The anesthetic will sting or burn when first injected. There will be a hard pressure sensation when the needle is inserted, and there is usually some brief pain when the needle goes through the meninges. (See CSF collection.) Overall, discomfort is minimal to moderate. The entire procedure usually takes about 30 minutes. The actual fluid collection only takes a few minutes. Why the test is performed: This test is performed to evaluate the following:
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