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Neonatal cystic fibrosis screening


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Neonatal cystic fibrosis screening

Alternative Names:

Cystic fibrosis screening - neonatal; Immunoreactive trypsinogen; IRT test
What the risks are:

Risks associated with the test include:

  • Infection (a slight risk any time the skin is broken)
  • Parental anxiety over false positive tests
  • False reassurance over false negative tests

Special considerations:

The IRT level does not indicate the severity of the CF. False-positives may occur.


References:
Gross, SD, Boyle, CA, Botkin, JR, et al. Newborn Screening for Cystic Fibrosis:Evaluation of Benefits and Risks and Recommendations for State Newborn Screening Programs. MMWR. 2004;53(RR13);1-36.
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